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CAROTENOIDS IN THE NEWS
In memory of Professor Dr. Hans-Dieter Martin
A new type of carotenoid has been synthesized with a 2H-pyran ring placed in the polyene chain. This compound was successively elongated by Wittig reactions. The pyran-carotenoids obtained show a significant increased λmax compared with carotenoids lacking the pyran ring. A further remarkable bathochromic shift was observed upon protonation to pyranium-carotenoids. The pyranium ring is the distinctive feature of anthocyanidin dyes and has now become an internal part of carotenoids. Eur. J. Chem. 2010, 435 – 439.
http://www3.interscience.wiley.com/cgi-bin/fulltext/...
Astaxanthin (1), a red-orange carotenoid pigment, is a powerful biological antioxidant that occurs naturally in a wide variety of living organisms. The potent antioxidant property of 1 has been implicated in its various biological activities demonstrated in both experimental animals and clinical studies. http://pubs.acs.org/doi/full/10.1021/np050354%2B
(3R,3′R,6′R)-Lutein (1) is a major dietary carotenoid that is abundant in most fruits and vegetables commonly consumed in the U.S. and that accumulates in the human plasma, major organs, and ocular tissues. Numerous epidemiological and experimental studies have shown that 1 has important biological activities and may play an important role in the prevention of age-related macular degeneration (AMD). A relatively straightforward methodology for the total synthesis of 1 and three of its stereoisomers has been developed. http://pubs.acs.org/doi/full/10.1021/jo900432r
Upcoming Conferences
The next Conference on Food Pigments will be held in Budapest, 20-24 June, 2010.
For more information click to visit the conference website here:
Macular Carotenoids & AMD, 2011
A conference for macular carotenoid researchers, exploring up-to-date and evidence-based hypotheses and the supporting research data into the role of the macular carotenoids in age-related macular degeneration (AMD). Downing College, University of Cambridge, UK 12 – 15 July 2011. Click to visit the conference website: http://suzy-howes.co.uk/macularcarotenoids/index.html
The 16th International Symposium on Carotenoids will be held in July 2011 in the World Heritage city of Krakow, Poland. Professor Kazimierz Strzalka at the Department of Biochemistry, Biophysics and Biotechnology, Jagiellonian University will be hosting this Symposium. Professor Strzalka and the local organizing committee will be creating a web site dedicated to the 2011 Symposium in the upcoming months
